Carbohydrate Counting at Meal Time Followed by a Small Secondary Postprandial...
When a meal has a high-carbohydrate and high-fat content using the carbohydrate counting method for insulin dose adjustments at mealtime and administering additional bolus insulin units 3 h later...
View ArticleThe Potential Effect of Ultra-Long Insulin Degludec on Glycemic Variability
Data from PK and PD studies combined with the results of several clinical trials suggest that IDeg has the potential to improve the management of T1D and T2D patients by allowing some flexibility in...
View ArticleEffect of Insulin Degludec vs Insulin Glargine U100 on Hypoglycemia in...
Among patients with type 1 diabetes and at least 1 risk factor for hypoglycemia, 32 weeks’ treatment with insulin degludec vs insulin glargine U100 resulted in a reduced rate of overall symptomatic...
View ArticleEffect of Insulin Degludec vs Insulin Glargine U100 on Hypoglycemia in...
Among patients with type 2 diabetes treated with insulin and with at least 1 hypoglycemia risk factor, 32 weeks’ treatment with insulin degludec vs insulin glargine U100 resulted in a reduced rate of...
View ArticleOvercoming clinical inertia in insulin initiation in primary care for...
Australian study – Stepping Up was associated with improved glycaemic control compared to usual care for 24 months, suggesting that the model facilitated more timely treatment intensification. Ongoing...
View ArticleInsulin identification checker
This resource has been created to assist pharmacists and their relevant members of staff, for example an accuracy checking technician (ACT), with selecting the correct insulin for dispensing against...
View ArticleWhat determines treatment satisfaction of patients with type 2 diabetes on...
A number of factors including diabetes education, perceived and actual hyperglycaemia and macrovascular complications are associated with treatment satisfaction. Self-management education programmes...
View ArticleSystematic review of metformin monotherapy and dual therapy with sodium...
The combined therapy of SGLT2 inhibitor along with metformin is more effective in HbA1c reduction and weight reduction as compared to monotherapy using metformin alone. Among the three SGLT2 inhibitors...
View ArticleHypoglycemia After Initiation of Basal Insulin in Patients with Type 2...
US patients with T2D who experienced hypoglycemia within 6 months of basal insulin initiation were more likely to discontinue treatment, accompanied by a greater healthcare burden (Advances in Therapy)
View ArticleThe Risks of Nocturnal Hypoglycaemia in insulin-treated diabetes
The morbidity and mortality associated with nocturnal hypoglycaemia is probably much greater than realised, causing seizures, coma and cardiovascular events and affects quality of life, mood and work...
View ArticleInsulin regimens and glycemic control in different parts of Europe over 4...
When starting insulin, HbA1c and prevalence of complications were higher in EEur. Regional differences exist in choice of insulin regimens in Europe. However, people starting insulin improved and...
View ArticleInsulin regimens and glycemic control in different parts of Europe over 4...
When starting insulin, HbA1c and prevalence of complications were higher in EEur. Regional differences exist in choice of insulin regimens in Europe. However, people starting insulin improved and...
View ArticleEffects of Sotagliflozin Added to Insulin in Patients with Type 1 Diabetes
Among patients with type 1 diabetes who were receiving insulin, the proportion of patients who achieved a glycated hemoglobin level lower than 7.0% with no severe hypoglycemia or diabetic ketoacidosis...
View ArticleInsulin Therapy Increases Cardiovascular Risk: Time for a Sea of Change in...
These associations support the findings of large-scale evaluations that strongly suggest that insulin therapy has a poorer short- and long-term safety profile than that found to many other anti-T2D...
View ArticleAssociation of Insulin Pump Therapy vs Insulin Injection Therapy With Severe...
Among young patients with type 1 diabetes, insulin pump therapy, compared with insulin injection therapy, was associated with lower risks of severe hypoglycemia and diabetic ketoacidosis and with...
View ArticleEffect of adding GLP-1RA on mortality, cardiovascular events and metabolic...
Based on a large UK cohort in routine clinical practice, adding a GLP-1RA to insulin therapy is associated with a reduction in risk of composite CV events and all-cause mortality, but non-significant...
View ArticlePrimary care physician perspectives on basal insulin initiation and...
Study results identify additional opportunities for assisting patients in making the transition to insulin, including more frequent direct outreach to monitor insulin usage (Primary Care Diabetes)
View ArticleEffect of Oral Insulin on Prevention of Diabetes in Relatives of Patients...
Among autoantibody-positive relatives of patients with type 1 diabetes, oral insulin at a dose of 7.5 mg/d, compared with placebo, did not delay or prevent the development of type 1 diabetes over 2.7...
View ArticleGlycaemic responses in Asian and non-Asian people with type 2 diabetes...
In our post-hoc meta-analysis, Gla-100 effectively lowers HbA1c and FPG in Asian patients with type 2 diabetes (T2D) uncontrolled on OADs with similar incidence of hypoglycaemia and less absolute...
View ArticleLower Mean Blood Glucose during Short-term Intensive Insulin Therapy is...
Stricter glycemic control during short-term intensive insulin therapy produced more remission despite self-manageable hypoglycemia. Based on glycemic parameters in the middle mean tertile, we propose...
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